Description :

Although a drug may kill some cancer cells almost invariably a subset of them will be resistant and survive the treatment cancers often have multiple mechanisms for surviving and growing which may change over time and in response to treatment. Cancer drug resistance one of the main causes of failure in the treatment of cancer is the development of drug resistance by the cancer cells this is a very serious problem that may lead to recurrence of disease or even death this section is intended to introduce some of the main ways in which cancer cells can resist treatments. Comprehensive reviews written by renowned experts provide great insight on the current knowledge on drug resistance mechanisms this book is a ready source of information to clinicians cell and cancer biologists and defines molecular drug resistance mechanisms that are challenging scientists and clinical oncologists today about editors. In addition to arising through genetic alterations drug resistance can also emerge as a result of alterations in cancer cells epigenetic codes molecular modifications that without altering the dna code turn genes on or off a major difference between epigenetics and genetics is that the epigenetic code is reversible and can shift over time